Publications

Dale, Jahrane A., Stephen L. Schmidt, Kyle T. Mitchell, Jennifer J. Peters, Dennis A. Turner, and Warren M. Grill. “Mechanisms mediating dynamic changes in neural responses during deep brain stimulation.” Brain Stimul 19, no. 1 (December 10, 2025): 103002. https://doi.org/10.1016/j.brs.2025.103002.

Marshall, Daniel P., Elie S. Farah, Eric D. Musselman, Nicole A. Pelot, and Warren M. Grill. “PyFibers: An open-source NEURON-Python package to simulate responses of model nerve fibers to electrical stimulation.” PLoS Computational Biology 21, no. 12 (December 2025): e1013764. https://doi.org/10.1371/journal.pcbi.1013764.

Rodriguez Capilla, Rocio, Aislinn M. Hurley, Karthik Kumaravelu, Jennifer J. Peters, Hui-Jie Lee, Dennis A. Turner, Warren M. Grill, and Stephen L. Schmidt. “Effect of frequency on dual target deep brain stimulation.” Clin Neurophysiol 182 (December 1, 2025): 2111467. https://doi.org/10.1016/j.clinph.2025.2111467.

Barth, Bradley B., and Warren M. Grill. “Burst-patterned stimulation restores colonic motility in preclinical models.” Science Translational Medicine 17, no. 823 (November 2025): eadu4615. https://doi.org/10.1126/scitranslmed.adu4615.

Meijs, Suzan, Matthew Bryson, and Warren M. Grill. “Fidelity of dorsal column axon activity in response to clinical spinal cord stimulation paradigms.” Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2025 (July 2025): 1–5. https://doi.org/10.1109/embc58623.2025.11254685.

Atchuthan, Nickolaj Ajay, Warren M. Grill, and Suzan Meijs. “Exploring Tonic and Burst Stimulation in Neural Fibers: A Computational Modeling Approach.” Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2025 (July 2025): 1–6. https://doi.org/10.1109/embc58623.2025.11253067.

Wei, Xuefeng, Wali Sohail, Nikhil Parab, Allen Hong, and Warren M. Grill. “Simulation of Spatiotemporal Current Density Distribution on Electrode-Electrolyte Interface during Deep Brain Stimulation.” Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2025 (July 2025): 1–5. https://doi.org/10.1109/embc58623.2025.11253017.

Musselman, Eric D., Ishani Raha, Nicole A. Pelot, and Warren M. Grill. “Scaling of vagus nerve stimulation parameters does not achieve equivalent nerve responses across species.” Bioelectronic Medicine 11, no. 1 (May 2025): 11. https://doi.org/10.1186/s42234-025-00174-9.

Peña, Edgar, Nicole A. Pelot, and Warren M. Grill. “Ramped kilohertz-frequency signals produce nerve conduction block without onset response.” Journal of Neural Engineering 22, no. 3 (May 2025). https://doi.org/10.1088/1741-2552/add20e.

Pelot, Nicole A., Boshuo Wang, Daniel P. Marshall, Minhaj A. Hussain, Eric D. Musselman, Gene J. Yu, Jahrane Dale, et al. “Guidance for sharing computational models of neural stimulation: from project planning to publication.” Journal of Neural Engineering 22, no. 2 (March 2025). https://doi.org/10.1088/1741-2552/adb997.

Thio, Brandon J., Nishant Sinha, Kathryn A. Davis, Saurabh R. Sinha, and Warren M. Grill. “Stereo-EEG propagating source reconstruction identifies new surgical targets for epilepsy patients.” Brain : A Journal of Neurology 148, no. 3 (March 2025): 764–75. https://doi.org/10.1093/brain/awae297.

Kumaravelu, Karthik, Stephen L. Schmidt, Yi Zhao, Allison Vittert, Brandon D. Swan, Chintan S. Oza, Jennifer J. Peters, Kyle T. Mitchell, Dennis A. Turner, and Warren M. Grill. “Analyses of biomarkers for tremor using local field potentials recorded from deep brain stimulation electrodes in the thalamus.” Brain Stimul 18, no. 5 (2025): 1479–89. https://doi.org/10.1016/j.brs.2025.08.006.

Martinez-Nunez, Alfonso Enrique, Christopher J. Rozell, Simon Little, Huiling Tan, Stephen L. Schmidt, Warren M. Grill, Miroslav Pajic, et al. “Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications.” Front Hum Neurosci 19 (2025): 1544994. https://doi.org/10.3389/fnhum.2025.1544994.

Wang, Boshuo, Minhaj A. Hussain, Torge Worbs, Axel Thielscher, Warren M. Grill, and Angel V. Peterchev. “Single pointwise samples of electric field on a neuron model cannot predict activation threshold by brain stimulation.” Brain Stimul 18, no. 5 (2025): 1667–70. https://doi.org/10.1016/j.brs.2025.08.025.

Martinez-Nunez, Alfonso Enrique, Christopher J. Rozell, Simon Little, Huiling Tan, Stephen L. Schmidt, Warren M. Grill, Miroslav Pajic, et al. “Corrigendum: Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications.” Front Hum Neurosci 19 (2025): 1612584. https://doi.org/10.3389/fnhum.2025.1612584.

Grill, Warren M., and Nicole A. Pelot. “Computational modeling of autonomic nerve stimulation: Vagus et al.” Current Opinion in Biomedical Engineering 32 (December 2024): 100557. https://doi.org/10.1016/j.cobme.2024.100557.

Yu, Gene J., Federico Ranieri, Vincenzo Di Lazzaro, Marc A. Sommer, Angel V. Peterchev, and Warren M. Grill. “Circuits and mechanisms for TMS-induced corticospinal waves: Connecting sensitivity analysis to the network graph.” PLoS Comput Biol 20, no. 12 (December 2024): e1012640. https://doi.org/10.1371/journal.pcbi.1012640.

Thio, Brandon J., Nathan D. Titus, Nicole A. Pelot, and Warren M. Grill. “Reverse-engineered models reveal differential membrane properties of autonomic and cutaneous unmyelinated fibers.” PLoS Computational Biology 20, no. 10 (October 2024): e1012475. https://doi.org/10.1371/journal.pcbi.1012475.

Hussain, Minhaj A., Warren M. Grill, and Nicole A. Pelot. “Highly efficient modeling and optimization of neural fiber responses to electrical stimulation.” Nature Communications 15, no. 1 (August 2024): 7597. https://doi.org/10.1038/s41467-024-51709-8.

Dong, Ping, Konstantin Bakhurin, Yuhui Li, Mohamad A. Mikati, Jianmin Cui, Warren M. Grill, Henry H. Yin, and Huanghe Yang. “Attenuating midline thalamus bursting to mitigate absence epilepsy.” Proc Natl Acad Sci U S A 121, no. 28 (July 9, 2024): e2403763121. https://doi.org/10.1073/pnas.2403763121.

Li, Yuhui, Sung-Ho Lee, Chunxiu Yu, Li-Ming Hsu, Tzu-Wen W. Wang, Khoa Do, Hyeon-Joong Kim, Yen-Yu Ian Shih, and Warren M. Grill. “Optogenetic fMRI reveals therapeutic circuits of subthalamic nucleus deep brain stimulation.” Brain Stimulation 17, no. 4 (July 2024): 947–57. https://doi.org/10.1016/j.brs.2024.07.022.

Wang, Boshuo, Angel V. Peterchev, Gabriel Gaugain, Risto J. Ilmoniemi, Warren M. Grill, Marom Bikson, and Denys Nikolayev. “Quasistatic approximation in neuromodulation.” ArXiv, April 23, 2024.

Schmidt, Stephen L., Afsana H. Chowdhury, Kyle T. Mitchell, Jennifer J. Peters, Qitong Gao, Hui-Jie Lee, Katherine Genty, et al. “At home adaptive dual target deep brain stimulation in Parkinson's disease with proportional control.” Brain 147, no. 3 (March 1, 2024): 911–22. https://doi.org/10.1093/brain/awad429.

Peña, Edgar, Nicole A. Pelot, and Warren M. Grill. “Computational models of compound nerve action potentials: Efficient filter-based methods to quantify effects of tissue conductivities, conduction distance, and nerve fiber parameters.” PLoS Computational Biology 20, no. 3 (March 2024): e1011833. https://doi.org/10.1371/journal.pcbi.1011833.

Kumaravelu, Karthik, and Warren M. Grill. “Neural mechanisms of the temporal response of cortical neurons to intracortical microstimulation.” Brain Stimulation 17, no. 2 (March 2024): 365–81. https://doi.org/10.1016/j.brs.2024.03.012.